Are you working for the same client before the work location change and after?
Also does the old work location and new work location are in same Metroplitan Statistical Area?
You can go out from USA but while returning back you need to go for stamping. And as you said you applied for amendment you can go only for stamping once the amendment is approved.
when the question says "Do you have any earlier Visa rejections" it means when you attend the visa stamping at consulate and got rejected in your passport.
1) You need to provide the Vendor letter which has your name stating that your actual employer is your employer name
2) Salary can be more than LCA but not less
3) Each I 797 is each H1B